Image of influenza virus shattering glass pancreas

In patients with diabetes

Flu Can Have A Devastating Impact1

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Your patients with diabetes are at increased risk of dangerous complications when diagnosed with influenza2-4

Patients living with diabetes are at increased risk for influenza complications2-4

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~3x  (95% CI: 2.04-4.71)

more likely to be hospitalized2

~4x  (95% CI: 1.29-14.3)

more likely to be admitted to the ICU2

Study design2

Subjects: 162 patients aged <1 to 85 years

Study period: May 25–July 1, 2009

Study limitations: This study was limited to those with PCR-confirmed influenza A H1N1. Medical history was obtained solely by patient interview.

~2x  (95% CI: 1.5-3.6)

more likely to die after influenza hospitalization4

Study design4

Subjects: 196 patients aged 18 and older

Study period: April 29, 2009–March 31, 2010

Study limitations: Underreporting and misclassification of outcome or risk factors are possible and might conceal the real disease burden. Study period was during H1N1 pandemic.

74%  (95% CI: 2.15-3.74, p<0.05)

increase in abnormal glycemic events5

Study design: Patient generated health data and medical claims were analyzed for 167,672 patients aged 18 and older

Study Period: 2016–2017 influenza season

Study limitations: The analysis focused on adults with commercial insurance and does not fully represent older people with diabetes within the United States or at-risk underserved populations.

The American Diabetes Association® urges eligible individuals aged 6 months and older to get their annual flu shot6

Protecting against influenza can help your patients with diabetes avoid influenza-related complications, such as hospitalization and death.2-4,7


  •  Estimated flu-related illnesses, medical visits, hospitalizations, and deaths in the United States — 2019–2020 flu season. Centers for Disease Control and Prevention. October 1, 2021. Accessed November 11, 2021. 
  •  Allard R, Leclerc P, Tremblay C, Tannenbaum T-N. Diabetes and the severity of pandemic influenza A (H1N1) infection. Diabetes Care. 2010;33:1491-1493. 
  •  Hulme KD, Gallo LA, Short KR. Influenza virus and glycemic variability in diabetes: a killer combination? Front Microbiol. 2017;8:861. 
  •  Wilking H, Buda S, von der Lippe E, et al. Mortality of 2009 pandemic influenza A(H1N1) in Germany. Euro Surveill. 2010;15. pii:19741. 
  •  Samson SI, Konty K, Lee W, et al. Quantifying the impact of influenza among persons with type 2 diabetes mellitus: a new approach to determine medical and physical activity impact. J Diabetes Sci Technol. 2019;15(1):44-52. 
  •  Top health organizations urge flu and COVID-19 vaccines to protect vulnerable, reduce burden on hospitals. American Heart Association. September 27, 2021. Accessed November 11, 2021. 
  •  Vamos EP, Pape UJ, Curcin V, et al. Effectiveness of the influenza vaccine in preventing admission to hospital and death in people with type 2 diabetes. CMAJ. 2016;188(14):E342-E351.